Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666893 | 1.00 | CYP2C19 (1.00) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL1458057 | 1.00 | CYP2C19 (1.00) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL10959538 | 0.98 | CYP2C19 (0.96) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL1457969 | 0.98 | CYP2C19 (0.96) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL1458161 | 0.98 | CYP2C19 (0.96) | CYP2C19CYP2D6SRCPOLBLMNA | |
| Methyl Alcohol SCHEMBL11775681 | 0.96 | CYP2C19 (0.93) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL5156636 | 0.89 | CYP2C19 (0.80) | CYP2C19LMNA | |
| SCHEMBL5371218 | 0.88 | CYP2C19 (0.79) | CYP2C19CYP2D6SRCPOLBLMNA | |
| SCHEMBL6967261 | 0.86 | CYP2C19 (0.76) | CYP2C19CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL7469210 | 0.85 | CYP2C19 (0.73) | CYP2C19CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130204238-A1 | COMBINATION THERAPY | FOLLICA, INC (US) | 2013-08-08 | — | — | US | disclosed |
| EP-2552323-A1 | COMBINATION THERAPY | Follica, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2012125941-A1 | LITHIUM TREATMENT FOR MICROBIAL INFECTIONS | FOLLICA, INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012067631-A1 | BODY SURFACE TREATMENT | FOLLICA, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012067630-A1 | HAIR GROWTH TREATMENT | FOLLICA, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012067632-A1 | SEQUENTIAL BODY SURFACE TREATMENT | FOLLICA, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011123218-A1 | COMBINATION THERAPY | FOLLICA, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110130748-A1 | BODY SURFACE TREATMENT | FOLLICA, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20110130706-A1 | SEQUENTIAL BODY SURFACE TREATMENT | FOLLICA, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20110130711-A1 | HAIR GROWTH TREATMENT | FOLLICA, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20040009930-A1 | Macrolide antibiotics | PFIZER INC. | 2004-01-15 | — | — | US | disclosed |
| EP-1307468-A1 | MACROLIDE ANTIBIOTICS | Pfizer Products Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20020115621-A1 | Macrolide antibiotics | PFIZER INC. | 2002-08-22 | — | — | US | disclosed |
| WO-2002012260-A1 | MACROLIDE ANTIBIOTICS | PFIZER PRODUCTS INC. (US) | 2002-02-14 | — | — | WO | disclosed |
| US-5610164-A | (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| CN-1142498-A | (Thiophen-2-yl-)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PROD (US) | 1997-02-12 | — | — | CN | disclosed |
| EP-0755932-A1 | (Thiophen-2-yl)piperidin or tetrahydropyridin-azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0570507-A4 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | EP | disclosed |
| EP-0570507-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009930-A1 | Macrolide antibiotics | MRPL21, NOP2, NPPA | CYP2C19 435/4885CYP2D6 249/4885SRC 4815/4885 |
| US-20020115621-A1 | Macrolide antibiotics | MRPL21, NOP2, NPPA | CYP2C19 435/4885CYP2D6 249/4885SRC 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.