Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898193 | 1.00 | MMP2 (0.68) | MMP2 | |
| Trifluoroacetic Acid SCHEMBL5898481 | 0.97 | MMP2 (0.64) | MMP2 | |
| SCHEMBL5898338 | 0.94 | MMP2 (0.71) | MMP2 | |
| SCHEMBL7427057 | 0.93 | MMP2 (0.58) | MMP2 | |
| SCHEMBL5897916 | 0.93 | MMP2 (0.72) | MMP2 | |
| SCHEMBL6765725 | 0.93 | MMP2 (0.72) | MMP2 | |
| SCHEMBL6686352 | 0.92 | MMP2 (0.73) | MMP2 | |
| SCHEMBL5897850 | 0.92 | MMP2 (0.73) | MMP2 | |
| SCHEMBL7544962 | 0.92 | MMP2 (0.73) | MMP2 | |
| Trifluoroacetic Acid SCHEMBL5898211 | 0.91 | MMP2 (0.67) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263755-A2 | CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | Bristol-Myers Squibb Pharma Company (US) | 2002-12-11 | — | — | EP | claimed |
| WO-2001070673-A2 | CYCLIC β-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-$g(a) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-27 | — | — | WO | claimed |