Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226208 | 0.86 | HDAC1 (0.70) | PPARGNR1H4PPARANPC1HDAC2 | |
| SCHEMBL7302295 | 0.84 | SERPINE1 (0.65) | PPARGNR1H4SERPINE1NPC1HDAC2 | |
| SCHEMBL6107043 | 0.84 | PPARG (0.64) | PPARGNR1H4PPARASERPINE1NPC1 | |
| SCHEMBL6170145 | 0.82 | HDAC1 (0.66) | PPARGNR1H4PPARANPC1HDAC2 | |
| SCHEMBL1067039 | 0.81 | MEN1 (0.76) | NPC1HDAC2HDAC1ALDH1A1RAB9A | |
| SCHEMBL6109346 | 0.81 | SERPINE1 (0.77) | PPARGNR1H4PPARASERPINE1NPC1 | |
| SCHEMBL5223727 | 0.80 | PTGS1 (0.72) | NR1H4NPC1HDAC2HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6542790 | 0.80 | NPC1 (0.58) | PPARGNR1H4PPARASERPINE1NPC1 | |
| SCHEMBL5221185 | 0.78 | MEN1 (0.84) | PPARGNR1H4PPARASERPINE1NPC1 | |
| SCHEMBL5224928 | 0.78 | MEN1 (0.84) | PPARGNR1H4PPARASERPINE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |