Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301478 | 0.89 | HDAC1 (0.69) | SERPINE1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7303587 | 0.85 | RAB9A (0.68) | SERPINE1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7293409 | 0.84 | SERPINE1 (0.67) | SERPINE1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7292066 | 0.84 | KCNMA1 (0.69) | SERPINE1RAB9ANPC1SMN1; SMN2HSD17B2 | |
| SCHEMBL7428272 | 0.84 | PPARG (0.60) | SERPINE1RAB9ANPC1ALDH1A1GLA | |
| SCHEMBL7297665 | 0.82 | SERPINE1 (0.72) | SERPINE1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5226208 | 0.82 | HDAC1 (0.70) | RAB9ANPC1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL7302951 | 0.81 | SERPINE1 (0.71) | SERPINE1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6170145 | 0.81 | HDAC1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1NR1H4 | |
| SCHEMBL5223727 | 0.79 | PTGS1 (0.72) | RAB9ANPC1ALDH1A1GLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |