Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.54 |
| ▸ | CTSL | P07711 | 14/20 | 0.54 |
| ▸ | CTSS | P25774 | 13/20 | 0.54 |
| ▸ | CTSB | P07858 | 6/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428335 | 0.85 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5098859 | 0.84 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7426104 | 0.83 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7429565 | 0.83 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105583 | 0.82 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6403850 | 0.82 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4686330 | 0.82 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6403854 | 0.81 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7430841 | 0.80 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6700166 | 0.80 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | claimed |