Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427702 | 0.94 | ITGB3 (0.73) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7433090 | 0.93 | ITGB3 (0.76) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7399141 | 0.93 | ITGB3 (0.68) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7390053 | 0.92 | ITGB3 (0.80) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7398467 | 0.91 | ITGB3 (0.66) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7431646 | 0.89 | ITGB3 (0.85) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7390269 | 0.87 | ITGB3 (0.73) | ITGB3ITGA2BRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7394021 | 0.86 | ITGB3 (0.86) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7395631 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7387428 | 0.85 | ITGB3 (0.85) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |