Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 13/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882140 | 1.00 | IL6ST (0.50) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL2882143 | 1.00 | IL6ST (0.50) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL5520510 | 0.92 | IL6ST (0.51) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL8030490 | 0.91 | IL6ST (0.52) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL8030492 | 0.91 | IL6ST (0.52) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL8500845 | 0.84 | IL6ST (0.56) | IL6STSTAT3PIK3CDNAAA | |
| SCHEMBL8500848 | 0.84 | IL6ST (0.56) | IL6STSTAT3PIK3CDNAAA | |
| SCHEMBL12202967 | 0.83 | IL6ST (0.51) | IL6STSTAT3FAAHPIK3CDMGLL | |
| SCHEMBL8220702 | 0.82 | PIK3CD (0.50) | IL6STSTAT3FAAHPIK3CDNAAA | |
| SCHEMBL6450650 | 0.82 | PIK3CD (0.50) | IL6STSTAT3FAAHPIK3CDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |