Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725035 | 0.85 | SIGMAR1 (0.62) | SIGMAR1GAAMAPTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7410846 | 0.84 | SIGMAR1 (0.60) | SIGMAR1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL7444132 | 0.81 | SIGMAR1 (0.47) | SIGMAR1GAAMAPTSMN1; SMN2GRIN2D | |
| SCHEMBL6719799 | 0.80 | GAA (0.54) | SIGMAR1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL6717017 | 0.79 | SIGMAR1 (0.73) | SIGMAR1MAPTLMNA | |
| SCHEMBL6719747 | 0.78 | SIGMAR1 (0.43) | SIGMAR1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL6719354 | 0.78 | SIGMAR1 (0.39) | SIGMAR1GAAMAPTLMNA | |
| SCHEMBL7070142 | 0.77 | GAA (0.41) | SIGMAR1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL6717146 | 0.77 | SIGMAR1 (0.51) | SIGMAR1GAAMAPTLMNA | |
| SCHEMBL6719727 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262568-A | Neuroprotective compounds, high binding affinity for phencyclidine, nervous system disorders | STATE OF OREGON (US) | 1993-11-16 | — | — | US | claimed |