Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725043 | 0.84 | SIGMAR1 (1.00) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| Hydrochloric Acid SCHEMBL7410848 | 0.83 | SIGMAR1 (0.98) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL7444136 | 0.80 | SIGMAR1 (0.77) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL6719755 | 0.78 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL7070147 | 0.77 | SIGMAR1 (0.58) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL6719232 | 0.76 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL6719736 | 0.76 | SIGMAR1 (0.68) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL6158218 | 0.76 | SIGMAR1 (1.00) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL6719807 | 0.75 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL6717017 | 0.74 | SIGMAR1 (0.73) | SIGMAR1TP53CYP2D6TSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262568-A | Neuroprotective compounds, high binding affinity for phencyclidine, nervous system disorders | STATE OF OREGON (US) | 1993-11-16 | — | — | US | claimed |