Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | GNRHR | P30968 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130265 | 0.88 | TAAR1 (0.41) | TAAR1SMN1; SMN2P2RX7 | |
| SCHEMBL145819 | 0.84 | SLC6A2 (0.40) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL27747471 | 0.82 | TAAR1 (0.55) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL1461202 | 0.81 | TAAR1 (0.45) | TAAR1SMN1; SMN2 | |
| SCHEMBL27747472 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL12157171 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL6284488 | 0.78 | STIM1 (0.39) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL19303142 | 0.78 | HSD11B1 (0.41) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL6287654 | 0.77 | STIM1 (0.38) | SLC6A2SLC6A4STIM1ORAI1TAAR1 | |
| SCHEMBL2031892 | 0.77 | MEN1 (0.40) | SLC6A2SLC6A4STIM1ORAI1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703726-B | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115703726-A | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2023-02-17 | — | — | CN | disclosed |
| EP-1240143-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. Carlsson Research AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046146-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2001-06-28 | — | — | WO | disclosed |