Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935284 | 0.96 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL234072 | 0.77 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL5935208 | 0.73 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL7429031 | 0.73 | SIGMAR1 (0.74) | SIGMAR1 | |
| SCHEMBL7442708 | 0.71 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL5935280 | 0.70 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL5935226 | 0.70 | SIGMAR1 (0.93) | SIGMAR1 | |
| SCHEMBL5935268 | 0.69 | SIGMAR1 (0.91) | SIGMAR1 | |
| SCHEMBL5935249 | 0.69 | SIGMAR1 (0.79) | SIGMAR1 | |
| SCHEMBL9242412 | 0.69 | CHRNB4 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571832-A | Nitrogen-containing cyclohetero alkylamino aryl derivatives for CNS disorders | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-11-05 | — | — | US | disclosed |