Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196951 | 0.89 | IDO1 (0.67) | IDO1MEN1KMT2AHRH3DRD2 | |
| SCHEMBL3886046 | 0.87 | CA1 (0.44) | IDO1MEN1KMT2AHRH3HTR2A | |
| SCHEMBL10772938 | 0.85 | IDO1 (0.57) | IDO1MEN1KMT2AHRH3DRD2 | |
| SCHEMBL28130088 | 0.85 | IDO1 (0.61) | IDO1MEN1KMT2AHRH3DRD2 | |
| SCHEMBL7239389 | 0.83 | MEN1 (0.46) | IDO1MEN1KMT2AHRH3DRD2 | |
| SCHEMBL198056 | 0.82 | IDO1 (0.58) | IDO1MEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL7449325 | 0.80 | TDP1 (0.61) | IDO1MEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL7448881 | 0.80 | TDP1 (0.61) | IDO1MEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL20127257 | 0.80 | IDO1 (0.61) | IDO1MEN1KMT2AHRH3DRD2 | |
| SCHEMBL8048487 | 0.80 | TDP1 (0.61) | IDO1MEN1KMT2AHRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |