Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430255 | 0.91 | ITGA4 (0.60) | ALDH1A1MEN1KMT2AATMITGA4 | |
| SCHEMBL7424439 | 0.84 | ITGA4 (0.63) | ALDH1A1MEN1KMT2AITGA4ITGB1 | |
| SCHEMBL7426829 | 0.82 | ITGA4 (0.63) | ITGA4ITGB1 | |
| SCHEMBL7535332 | 0.81 | ITGA4 (0.57) | ALDH1A1MEN1KMT2AITGA4ITGB1 | |
| SCHEMBL7429677 | 0.81 | ITGA4 (0.61) | ITGA4ITGB1 | |
| SCHEMBL7540244 | 0.80 | ITGA4 (0.63) | ALDH1A1MEN1KMT2AATMITGA4 | |
| SCHEMBL7425689 | 0.80 | ITGA4 (0.58) | ALDH1A1MEN1KMT2AATMITGA4 | |
| SCHEMBL7433657 | 0.80 | ITGA4 (0.60) | MEN1KMT2AITGA4ITGB1 | |
| SCHEMBL7420275 | 0.79 | ITGA4 (0.60) | ITGA4ITGB1 | |
| SCHEMBL7423191 | 0.79 | ITGA4 (0.58) | ALDH1A1ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |