Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GLS | O94925 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698001 | 0.92 | KDM4E (0.64) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL621968 | 0.84 | GLS (0.64) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL18157878 | 0.84 | GLS (0.69) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL6114878 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL5691487 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL11440000 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL6115144 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL6115309 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL6114777 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA | |
| SCHEMBL6115308 | 0.83 | GLS (0.58) | KDM4EGLSLMNAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379351-A1 | 1,4-Dihydropyridine derivatives | SYNPHAR LABORATORIES INC. (CA) | 1990-07-25 | — | — | EP | claimed |
| US-5120750-A | Hypotensive agent, antiulcer agent and antiinflammatory agent | SYNPHAR LABORATORIES, INC. (CA) | 1992-06-09 | — | — | US | disclosed |
| EP-0379351-A1 | 1,4-Dihydropyridine derivatives | SYNPHAR LABORATORIES INC. (CA) | 1990-07-25 | — | — | EP | disclosed |