SCHEMBL7429189

SCHEMBL7429189

Cc1ccccc1NC(=O)Nc1ccc(CC(=O)NCC2CCN(CC(=O)O)CC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 19/20 0.62
ITGA4 P13612 19/20 0.62
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7427882 0.90 ITGB1 (0.53) ITGB1ITGA4SMN1; SMN2
SCHEMBL7425032 0.87 ITGA4 (0.64) ITGB1ITGA4SMN1; SMN2
SCHEMBL7430000 0.86 ITGB1 (0.57) ITGB1ITGA4SMN1; SMN2
SCHEMBL7426837 0.82 ITGA4 (0.60) ITGB1ITGA4
SCHEMBL7419553 0.80 ITGB1 (0.74) ITGB1ITGA4
SCHEMBL7430173 0.78 ITGA4 (0.54) ITGB1ITGA4
SCHEMBL7429192 0.77 ITGB1 (0.53) ITGB1ITGA4SMN1; SMN2
SCHEMBL7425123 0.77 ITGB1 (0.72) ITGB1ITGA4
SCHEMBL29612679 0.75 ITGB1 (0.67) ITGB1ITGA4
SCHEMBL3485567 0.75 ITGB1 (0.67) ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999054321-A1 SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS AVENTIS PHARMA LIMITED (GB) 1999-10-28 WO disclosed