SCHEMBL7429233

SCHEMBL7429233

CCOC(=O)c1cc2cccc(OCc3ccccc3)c2n(Cc2cccc(C(=N)N)c2)c1=O

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.57
F2 P00734 3/20 0.49
MAOB P27338 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7432426 0.89 F10 (0.49) F10F2MRGPRX4
SCHEMBL7429228 0.84 F10 (0.69) F10F2MAOB
SCHEMBL7421334 0.76 F10 (0.58) F10F2MAOB
SCHEMBL7427280 0.76 F2 (0.55) F10F2MRGPRX4
SCHEMBL7431654 0.76 F10 (0.58) F10F2
SCHEMBL7539919 0.75 MAOB (0.40) MAOB
SCHEMBL6435748 0.73 F10 (1.00) F10F2
SCHEMBL7432408 0.72 F10 (0.70) F10F2MRGPRX4
Hydrochloric Acid SCHEMBL6435742 0.72 F10 (0.98) F10F2
SCHEMBL7430819 0.71 F2 (0.52) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107954-A1 2-OXO-$i(2H)-QUINOLINE DERIVATIVES MERCK PATENT GmbH (DE) 2001-06-20 EP disclosed
WO-2000012479-A1 2-OXO-2H-QUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2000-03-09 WO disclosed