Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421334 | 0.92 | F10 (0.58) | F10MAOBF2MEN1HSP90AA1 | |
| SCHEMBL7432408 | 0.89 | F10 (0.70) | F10F2PLA2G2A | |
| SCHEMBL7429233 | 0.84 | F10 (0.57) | F10MAOBF2 | |
| SCHEMBL7431654 | 0.82 | F10 (0.58) | F10F2 | |
| SCHEMBL7432329 | 0.81 | F10 (0.61) | F10F2 | |
| Acetic Acid SCHEMBL7717345 | 0.81 | F10 (0.95) | F10F2PLA2G2A | |
| SCHEMBL7429295 | 0.81 | F10 (0.59) | F10F2 | |
| SCHEMBL6435781 | 0.81 | F10 (0.82) | F10F2 | |
| SCHEMBL7539916 | 0.77 | MAOB (0.49) | F10MAOBMEN1HSP90AA1KMT2A | |
| SCHEMBL7423194 | 0.76 | F2 (0.67) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |