Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432683 | 0.99 | SIGMAR1 (0.59) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7438989 | 0.99 | SIGMAR1 (0.59) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| Hydrochloric Acid SCHEMBL7430264 | 0.99 | SIGMAR1 (0.55) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7435436 | 0.96 | SIGMAR1 (0.54) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| Hydrochloric Acid SCHEMBL7431292 | 0.94 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| Oxalic Acid SCHEMBL7445453 | 0.93 | SIGMAR1 (0.52) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| Oxalic Acid SCHEMBL7431270 | 0.93 | SIGMAR1 (0.52) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7429750 | 0.90 | SIGMAR1 (0.55) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7432021 | 0.90 | SLC6A2 (0.52) | SIGMAR1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7433683 | 0.90 | SIGMAR1 (0.65) | SIGMAR1SLC6A2SLC6A4SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559569-A1 | Central nervous system antiischemic agents | Bristol-Myers Squibb Company (US) | 1993-09-08 | — | — | EP | claimed |