Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441567 | 0.89 | METAP1 (0.43) | METAP1CYP1A2SIGMAR1METAP2 | |
| SCHEMBL4623479 | 0.89 | CYP1A2 (0.50) | METAP1CYP1A2SIGMAR1KDM4EMETAP2 | |
| SCHEMBL1111381 | 0.88 | METAP1 (0.46) | METAP1CYP1A2SIGMAR1KDM4EHPGD | |
| SCHEMBL13169084 | 0.88 | METAP1 (0.46) | METAP1CYP1A2SIGMAR1KDM4EHPGD | |
| SCHEMBL10763159 | 0.86 | METAP1 (0.48) | METAP1CYP1A2SIGMAR1KDM4EMETAP2 | |
| SCHEMBL14398008 | 0.86 | CYP1A2 (0.46) | METAP1CYP1A2SIGMAR1KDM4EMETAP2 | |
| SCHEMBL28126617 | 0.85 | METAP1 (0.41) | METAP1CYP1A2SIGMAR1KDM4EMETAP2 | |
| SCHEMBL7903931 | 0.85 | CYP1A2 (0.57) | METAP1CYP1A2SIGMAR1METAP2 | |
| SCHEMBL11739573 | 0.85 | METAP1 (0.42) | METAP1CYP1A2SIGMAR1KDM4EHPGD | |
| SCHEMBL2580715 | 0.84 | METAP1 (0.50) | METAP1CYP1A2SIGMAR1HPGDMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |