Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739573 | 0.98 | METAP1 (0.42) | METAP1THRBCYP1A2SIGMAR1KDM4E | |
| SCHEMBL7429602 | 0.88 | METAP1 (0.50) | METAP1CYP1A2SIGMAR1KDM4EHPGD | |
| SCHEMBL2952373 | 0.88 | — | — | |
| SCHEMBL101244 | 0.85 | SIGMAR1 (0.45) | METAP1THRBCYP1A2SIGMAR1ALDH1A1 | |
| SCHEMBL8585482 | 0.84 | SIGMAR1 (0.48) | METAP1CYP1A2SIGMAR1ALDH1A1EPHX1 | |
| SCHEMBL13169084 | 0.82 | METAP1 (0.46) | METAP1CYP1A2SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL10768147 | 0.80 | METAP1 (0.44) | METAP1CYP1A2SIGMAR1HPGDMETAP2 | |
| SCHEMBL14398008 | 0.80 | CYP1A2 (0.46) | METAP1CYP1A2SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL10763159 | 0.80 | METAP1 (0.48) | METAP1CYP1A2SIGMAR1KDM4ELMNA | |
| SCHEMBL28126617 | 0.79 | METAP1 (0.41) | METAP1CYP1A2SIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083887-B | Inhibit the compound of BTK and/or JAK3 kinase activity | 北京韩美药品有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-106065017-B | Inhibit the compound of BTK and/or JAK3 kinase activities | 北京韩美药品有限公司 | 2018-06-01 | — | — | CN | disclosed |
| EP-2958682-B1 | PRINTABLE RADIATION CURABLE BARRIER COATINGS | SUN CHEMICAL CORP (US) | 2018-04-25 | — | — | EP | disclosed |
| CN-104311573-B | Compounds that inhibit BTK and/or JAK3 kinase activity | 北京韩美药品有限公司 | 2017-12-15 | — | — | CN | disclosed |
| US-9701860-B2 | Printable radiation curable barrier coatings | SUN CHEMICAL CORPORATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160009939-A1 | PRINTABLE RADIATION CURABLE BARRIER COATINGS | SUN CHEMICAL CORPORATION (US) | 2016-01-14 | — | — | US | disclosed |
| EP-2279219-B1 | USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS | BASF SE (DE) | 2013-04-17 | — | — | EP | disclosed |
| US-20120157548-A1 | USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES | BASF SE (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20110040030-A1 | USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS | BASF SE (DE) | 2011-02-17 | — | — | US | disclosed |
| EP-2279219-A1 | USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS | BASF SE (DE) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009138387-A1 | USE OF A CYCLOHEXANE DIOL MIXTURE FOR MANUFACTURING POLYMERS | BASF SE (DE) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157548-A1 | USE OF CYCLOALIPHATIC DIOLS AS BIOCIDES | DDT, DBH, GABBR1 | METAP1 1670/4885THRB 1764/4885CYP1A2 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.