Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 1/20 | 0.53 |
| ▸ | SELE | P16581 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435457 | 0.88 | SELP (0.56) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7429412 | 0.86 | SELP (0.54) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7437076 | 0.86 | SELP (0.54) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7438805 | 0.86 | SELP (0.54) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7440627 | 0.84 | SELP (0.52) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7430180 | 0.83 | SELP (0.51) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7425861 | 0.81 | SELP (0.60) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL7439282 | 0.78 | KMT2A (0.53) | HCAR2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7433330 | 0.75 | SELP (0.43) | SELPSELEPOLBHCAR2NPC1 | |
| SCHEMBL14015953 | 0.73 | SELP (0.69) | SELPSELEPOLBHCAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |