Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435457 | 0.87 | SELP (0.56) | SELPSELERAB9AHCAR2NPC1 | |
| SCHEMBL7436413 | 0.84 | SELP (0.46) | SELPSELERAB9AHCAR2NPC1 | |
| SCHEMBL7439282 | 0.84 | KMT2A (0.53) | RAB9AHCAR2NPC1CYP2C8CYP2C9 | |
| SCHEMBL7433961 | 0.82 | ABCC1 (0.47) | RAB9AHCAR2NPC1ALDH1A1KDM4E | |
| SCHEMBL7428881 | 0.80 | KDM4E (0.56) | RAB9AHCAR2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7431963 | 0.80 | KDM4E (0.54) | RAB9AHCAR2NPC1POLBALDH1A1 | |
| SCHEMBL7431684 | 0.79 | GAA (0.52) | RAB9ANPC1POLBLMNAMEN1 | |
| SCHEMBL7430649 | 0.79 | SELL (0.56) | SELPSELERAB9ANPC1ALDH1A1 | |
| SCHEMBL7429346 | 0.79 | SELL (0.45) | SELPSELERAB9ANPC1CYP2C9 | |
| SCHEMBL7437982 | 0.79 | POLB (0.44) | SELPSELERAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |