SCHEMBL742974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2761887	0.98	ALDH1A1 (0.56)	ALDH1A1DAOWDR91HDAC6F10
	SCHEMBL3309101	0.89	ALDH1A1 (0.64)	ALDH1A1DAOWDR91HDAC6KDM4E
	SCHEMBL3313449	0.86	ALDH1A1 (0.56)	ALDH1A1DAOWDR91HDAC6F10
	SCHEMBL10513283	0.86	WDR91 (0.50)	ALDH1A1DAOWDR91HDAC6F10
	SCHEMBL1174522	0.85	HDAC6 (0.53)	ALDH1A1DAOWDR91HDAC6F10
	Hydrochloric Acid SCHEMBL10514992	0.84	WDR91 (0.49)	ALDH1A1DAOWDR91HDAC6F10
	SCHEMBL31609056	0.83	ALDH1A1 (0.51)	ALDH1A1DAOWDR91HDAC6KDM4E
	Lithium Ion SCHEMBL742973	0.83	WDR91 (0.48)	ALDH1A1DAOWDR91HDAC6F10
	SCHEMBL30861168	0.79	ALDH1A1 (0.56)	ALDH1A1DAOHDAC6KDM4EHPGD
	SCHEMBL12922700	0.79	KDM4E (0.48)	ALDH1A1WDR91HDAC6F10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.