Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.60 |
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318246 | 1.00 | PREP (0.60) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL25678381 | 0.96 | FKBP1A (0.62) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL10522061 | 0.96 | PREP (0.64) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL29510776 | 0.95 | FKBP1A (0.61) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL30863413 | 0.93 | PREP (0.54) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL159104 | 0.91 | KLK7 (0.66) | PREPKLK7KLK5FKBP1A | |
| SCHEMBL5970730 | 0.91 | KLK7 (0.66) | PREPKLK7KLK5FKBP1A | |
| SCHEMBL159105 | 0.91 | KLK7 (0.66) | PREPKLK7KLK5FKBP1A | |
| SCHEMBL16272917 | 0.87 | FKBP1A (0.66) | PREPKLK7KLK5FKBP1ANPSR1 | |
| SCHEMBL7326760 | 0.87 | FKBP1A (0.66) | PREPKLK7KLK5FKBP1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1328278-C | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2007-07-25 | — | — | CN | disclosed |
| CN-1265661-A | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-0267723-B1 | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5364848-A | Elastase inhibitors | MERCK & CO., INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5132301-A | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-4954158-A | INHIBIT ETHYLENE PRODUCTION IN PLANTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1990-09-04 | — | — | US | disclosed |
| WO-1990007260-A2 | 2,3-METHANOPROLINE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| EP-0267723-A2 | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO. INC. (US) | 1988-05-18 | — | — | EP | disclosed |