Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.56 |
| ▸ | PTGIR | P43119 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 17/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054979 | 0.84 | PTGIR (0.69) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL27274388 | 0.82 | MLLT1 (0.53) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL4035161 | 0.80 | PTGIR (0.61) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL7855988 | 0.79 | PTGIR (0.50) | MLLT1PTGIRWDR5 | |
| SCHEMBL7855984 | 0.79 | PTGIR (0.50) | MLLT1PTGIRWDR5 | |
| SCHEMBL4032956 | 0.79 | PTGIR (0.62) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL27275424 | 0.78 | ADRA2A (0.77) | PTGIRADRA2AADRA2BADRA2C | |
| SCHEMBL10800812 | 0.77 | PTGIR (0.83) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL26703926 | 0.77 | PTGIR (0.61) | MLLT1PTGIRWDR5ADRA2AADRA2B | |
| SCHEMBL17186490 | 0.77 | PTGIR (0.61) | MLLT1PTGIRWDR5ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259485-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064643-A2 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-09-07 | — | — | WO | disclosed |