⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429749 | 0.83 | — | — | |
| Iodide SCHEMBL7434001 | 0.82 | — | — | |
| SCHEMBL10872426 | 0.79 | GBA1 (0.30) | — | |
| SCHEMBL7428749 | 0.78 | GBA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL9827936 | 0.78 | GBA1 (0.35) | — | |
| SCHEMBL7426772 | 0.76 | — | — | |
| SCHEMBL7430568 | 0.75 | HRH4 (0.37) | — | |
| SCHEMBL10872427 | 0.75 | HRH2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL10872130 | 0.75 | HRH2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL10874377 | 0.73 | HRH2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | claimed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | claimed |
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | disclosed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | disclosed |