Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648782 | 0.83 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8795722 | 0.79 | SMN1; SMN2 (0.59) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10535907 | 0.77 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10720726 | 0.77 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11684240 | 0.77 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6006301 | 0.76 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8795716 | 0.76 | SMN1; SMN2 (0.55) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL21629502 | 0.76 | SMN1; SMN2 (0.55) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27878111 | 0.75 | SMN1; SMN2 (0.58) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL20509384 | 0.74 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |