Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410505 | 0.98 | ACE2 (0.39) | ACE2LMNATSHRGPR84SPHK1 | |
| SCHEMBL15873883 | 0.98 | ACE2 (0.39) | ACE2LMNATSHRGPR84SPHK1 | |
| SCHEMBL7508844 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL296641 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL7507885 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL23925000 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL7517657 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL9544422 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL7509645 | 0.91 | ACE2 (0.52) | ACE2GPR84SPHK1FFAR1HMGCR | |
| SCHEMBL1410794 | 0.91 | TSHR (0.39) | ACE2LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537717-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | claimed |