Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509645 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL296641 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL7507885 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL7508844 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL9544422 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL23925000 | 1.00 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL7430855 | 0.91 | ACE2 (0.42) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL1826414 | 0.91 | ACE2 (0.52) | ACE2GPR84FFAR1SPHK1MAPT | |
| SCHEMBL15873883 | 0.89 | ACE2 (0.39) | ACE2GPR84FFAR1SPHK1OPRM1 | |
| SCHEMBL1410505 | 0.89 | ACE2 (0.39) | ACE2GPR84FFAR1SPHK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730860-B1 | Mixed micelles | HOFFMANN LA ROCHE (CH) | 2002-01-02 | — | — | EP | disclosed |
| US-5747066-A | PHOSPHATIDES, BILE ACID SALT OR DIHEXANOYLLECITHIN | HOFFMANN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0730860-A2 | Mixed micelles | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-11 | — | — | EP | disclosed |