Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.51 |
| ▸ | F10 | P00742 | 8/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427295 | 0.89 | F10 (0.64) | F2F10PRSS1 | |
| SCHEMBL7426338 | 0.83 | F10 (0.61) | F2F10PRSS1 | |
| SCHEMBL7428858 | 0.79 | F10 (0.59) | F2F10PRSS1 | |
| SCHEMBL7427330 | 0.75 | F10 (0.67) | F2F10PRSS1 | |
| SCHEMBL7426629 | 0.73 | F10 (0.48) | F2F10PRSS1 | |
| SCHEMBL7432329 | 0.72 | F10 (0.61) | F2F10PRSS1 | |
| SCHEMBL7431654 | 0.71 | F10 (0.58) | F2F10PRSS1 | |
| SCHEMBL7427399 | 0.71 | F10 (0.65) | F2F10PRSS1 | |
| SCHEMBL7429295 | 0.70 | F10 (0.59) | F2F10PRSS1 | |
| SCHEMBL7420509 | 0.69 | F10 (0.68) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |