Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384000 | 0.88 | TSHR (0.52) | L3MBTL1TSHRPKMTDP1CETP | |
| SCHEMBL7377074 | 0.88 | L3MBTL1 (0.56) | L3MBTL1TSHRPKMFFAR1IDO1 | |
| SCHEMBL85540 | 0.84 | TSHR (0.63) | TSHRFOLH1CETPIDO1 | |
| SCHEMBL10453287 | 0.83 | L3MBTL1 (0.56) | L3MBTL1PKMFOLH1FFAR1IDO1 | |
| SCHEMBL9555706 | 0.81 | CA1 (0.46) | L3MBTL1TSHRPKMTDP1FFAR1 | |
| SCHEMBL5552737 | 0.79 | L3MBTL1 (0.55) | L3MBTL1PKMFOLH1FFAR1IDO1 | |
| SCHEMBL16394878 | 0.78 | TSHR (0.52) | L3MBTL1TSHRPKMCETPIDO1 | |
| SCHEMBL9555702 | 0.77 | L3MBTL1 (0.43) | L3MBTL1TSHRPKMTDP1IDO1 | |
| SCHEMBL11288205 | 0.76 | TSHR (0.53) | TSHRFOLH1CETP | |
| SCHEMBL5552741 | 0.76 | L3MBTL1 (0.52) | L3MBTL1TSHRFOLH1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211220-A1 | Pyridazo[1,2-a][1,2]diazepine derivatives, intermediate products, process for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1987-02-25 | — | — | EP | disclosed |