Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364457 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL6578377 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL6578404 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL9635419 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL10589936 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL9634023 | 0.98 | CA2 (0.53) | CA2ACE2GPR84FFAR1FAAH | |
| Hydrochloric Acid SCHEMBL10655500 | 0.96 | CA2 (0.52) | CA2ACE2GPR84FFAR1FAAH | |
| SCHEMBL5127157 | 0.94 | CA2 (0.42) | CA2ACE2GPR84FFAR1MAPT | |
| SCHEMBL6934813 | 0.89 | CA2 (0.41) | CA2ACE2GPR84FFAR1MAPT | |
| SCHEMBL1620572 | 0.85 | CHRM1 (0.37) | CA2ACE2GPR84FFAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |