Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.77 |
| ▸ | MAOB | P27338 | 12/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852226 | 0.88 | MAOB (0.68) | ACHEMAOBTDP1MAOA | |
| SCHEMBL5617972 | 0.87 | ACHE (1.00) | ACHEMAOBMAOA | |
| SCHEMBL123187 | 0.84 | MAOB (0.68) | ACHEMAOBTDP1MAOA | |
| SCHEMBL5618373 | 0.81 | ACHE (0.77) | ACHEMAOBMAOA | |
| SCHEMBL7432074 | 0.81 | ACHE (1.00) | ACHEMAOBMAOA | |
| SCHEMBL11886594 | 0.80 | MAOB (0.71) | ACHEMAOBTDP1MAOA | |
| SCHEMBL7302411 | 0.79 | ACHE (0.65) | ACHEMAOBMAOA | |
| SCHEMBL16516507 | 0.79 | CA12 (0.65) | ACHEMAOBTDP1MAOA | |
| SCHEMBL6597080 | 0.78 | TDP1 (0.49) | ACHEMAOBTDP1 | |
| SCHEMBL5617624 | 0.78 | MAOB (1.00) | ACHEMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363793-B1 | ARYL ALKOXY COUMARINS, PROCESS FOR THEIR PRODUCTION AND THERAPEUTIC AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5100914-A | Monoamine Oxidase Inhibitors, Central Nervous System Disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0363793-A1 | Aryl alkoxy coumarins, process for their production and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |