Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.46 |
| ▸ | ATF4 | P18848 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740563 | 0.88 | F10 (0.43) | F10ATF4ANO1 | |
| SCHEMBL740808 | 0.81 | F10 (0.44) | F10 | |
| SCHEMBL12095609 | 0.77 | F10 (0.39) | F10ATF4ANO1ABL1 | |
| SCHEMBL4083820 | 0.76 | F10 (0.65) | F10 | |
| SCHEMBL12035519 | 0.73 | F10 (0.65) | F10 | |
| SCHEMBL741538 | 0.73 | SMYD3 (0.46) | — | |
| SCHEMBL743062 | 0.72 | F10 (0.32) | F10 | |
| SCHEMBL739377 | 0.71 | F10 (0.44) | F10 | |
| SCHEMBL739706 | 0.70 | KMT2A (0.50) | — | |
| SCHEMBL12056214 | 0.69 | F10 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |