Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310154 | 0.86 | MEN1 (0.64) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL23975946 | 0.82 | MEN1 (0.59) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL2125145 | 0.82 | MEN1 (0.63) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL23975950 | 0.82 | MEN1 (0.59) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL4820385 | 0.81 | HSD17B10 (0.61) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4003494 | 0.81 | HSD17B10 (0.61) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2608526 | 0.81 | MEN1 (0.58) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL23986784 | 0.81 | MEN1 (0.59) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30225304 | 0.81 | MEN1 (0.58) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL16738057 | 0.80 | POLB (0.61) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283310-B1 | N-BENZHYDRYL-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5028610-A | Calcium Channel Blockers | SANKYO COMPANY LIMITED (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0283310-A1 | N-Benzhydryl-substituted heterocyclic derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-09-21 | — | — | EP | disclosed |