Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975946 | 1.00 | MEN1 (0.59) | MEN1KMT2AATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30225304 | 0.98 | MEN1 (0.58) | MEN1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL11310154 | 0.85 | MEN1 (0.64) | MEN1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL7433315 | 0.82 | MEN1 (0.61) | MEN1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL13255714 | 0.82 | HSD17B10 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL19675877 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8297644 | 0.81 | MEN1 (0.53) | MEN1KMT2AATMKDM4EMTOR | |
| SCHEMBL2125145 | 0.81 | MEN1 (0.63) | MEN1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL13255712 | 0.81 | HPGD (0.59) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL967254 | 0.80 | SMN1; SMN2 (0.63) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222483-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |