Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430981 | 0.99 | GRIN1 (0.61) | GRIN1GRIN2B | |
| SCHEMBL7431299 | 0.96 | GRIN1 (0.61) | GRIN1GRIN2B | |
| SCHEMBL467160 | 0.93 | GRIN1 (0.70) | GRIN1GRIN2B | |
| SCHEMBL8010239 | 0.92 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL8010301 | 0.92 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL7436253 | 0.90 | SIGMAR1 (0.60) | GRIN1GRIN2B | |
| SCHEMBL8012780 | 0.90 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL8010724 | 0.87 | SIGMAR1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL7433139 | 0.87 | GRIN1 (0.60) | GRIN1GRIN2B | |
| SCHEMBL11932470 | 0.85 | GRIN1 (0.58) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| US-6031099-A | Piperidine derivates having anxiolytic effect | H. LUNDBECK A/S (DK) | 2000-02-29 | — | — | US | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |