Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747636 | 0.89 | LIPE (0.67) | LIPEEGLN1 | |
| SCHEMBL14217210 | 0.84 | LIPE (0.72) | LIPEEGLN1 | |
| SCHEMBL744867 | 0.83 | LIPE (0.71) | LIPEEGLN1 | |
| SCHEMBL3752294 | 0.82 | LIPE (0.62) | LIPEEGLN1 | |
| SCHEMBL3752817 | 0.82 | LIPE (0.72) | LIPEEGLN1 | |
| SCHEMBL748171 | 0.81 | LIPE (0.68) | LIPEEGLN1 | |
| SCHEMBL745795 | 0.81 | LIPE (0.77) | LIPE | |
| SCHEMBL746926 | 0.81 | LIPE (0.67) | LIPEEGLN1 | |
| SCHEMBL745236 | 0.80 | LIPE (0.58) | LIPE | |
| SCHEMBL3747148 | 0.80 | LIPE (0.59) | LIPEEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430023-A1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-03-21 | — | — | EP | claimed |
| WO-2010130665-A1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-18 | — | — | WO | claimed |
| EP-2430023-A1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130665-A1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-18 | — | — | WO | disclosed |