Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277076 | 1.00 | P2RX1 (0.46) | P2RX1REN | |
| SCHEMBL7290665 | 1.00 | P2RX1 (0.46) | P2RX1REN | |
| SCHEMBL7282458 | 0.98 | P2RX1 (0.44) | P2RX1REN | |
| SCHEMBL7281025 | 0.98 | P2RX1 (0.44) | P2RX1REN | |
| SCHEMBL7284146 | 0.97 | P2RX1 (0.44) | P2RX1REN | |
| SCHEMBL8909157 | 0.89 | REN (0.55) | P2RX1REN | |
| SCHEMBL9800511 | 0.89 | REN (0.55) | P2RX1REN | |
| SCHEMBL7283971 | 0.88 | REN (0.42) | REN | |
| SCHEMBL7282601 | 0.88 | REN (0.42) | REN | |
| SCHEMBL7295284 | 0.86 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572909-A1 | Amino acid derivatives as renin inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-08 | — | — | EP | disclosed |
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |