Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846984 | 0.81 | EGLN1 (0.45) | POLBGAAEPHX2TSHRMAPT | |
| SCHEMBL7443456 | 0.80 | GAA (0.40) | POLBGAAEPHX2TSHRMAPT | |
| SCHEMBL7429768 | 0.79 | GAA (0.48) | GAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL22277145 | 0.79 | POLB (0.43) | POLBGAAEPHX2TSHRMAPT | |
| SCHEMBL16761793 | 0.77 | POLB (0.43) | POLBGAAEPHX2TSHRMAPT | |
| Glutarate SCHEMBL28926850 | 0.77 | TSHR (0.48) | POLBGAAEPHX2TSHRMAPT | |
| SCHEMBL1515417 | 0.77 | TSHR (0.54) | EPHX2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL409033 | 0.77 | MAPT (0.52) | EPHX2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL10701326 | 0.77 | PAM (0.46) | TSHRMAPTALDH1A1 | |
| SCHEMBL20460677 | 0.77 | POLB (0.48) | POLBGAAEPHX2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |