Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892685 | 0.68 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| Benzophenone SCHEMBL28180817 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL6061130 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL30536983 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL30537001 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL1074283 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL28491203 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| Benzophenone SCHEMBL17745 | 0.66 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBATMTDP1 | |
| SCHEMBL23189428 | 0.66 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL4783318 | 0.66 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1POLBSMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329070-B1 | Cardiotonic alkanoyl and aroyl oxazolones | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0329070-A1 | Cardiotonic alkanoyl and aroyl oxazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-23 | — | — | EP | disclosed |