Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.52 |
| ▸ | ITGAV | P06756 | 20/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445119 | 0.90 | ITGAV (0.64) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7433674 | 0.90 | ITGAV (0.64) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7436966 | 0.90 | ITGAV (0.64) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL14608716 | 0.85 | ITGAV (0.66) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL14608717 | 0.83 | ITGAV (0.68) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL5248211 | 0.82 | ITGAV (0.63) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL5251715 | 0.82 | ITGAV (0.63) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7434310 | 0.80 | ITGAV (0.63) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7434572 | 0.80 | ITGAV (0.63) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7434305 | 0.80 | ITGAV (0.63) | ITGB3ITGAVITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410526-B1 | BONE DISORDERS; RESTENOSIS; VISION DISORDERS; ANTICHOLESTEROL AGENTS; ANTICANCER, ANTITUMOR AGENTS | MERCK & CO., INC. | 2002-06-25 | — | — | US | disclosed |