Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678864 | 1.00 | POLB (0.61) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL23485199 | 1.00 | POLB (0.61) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL30564487 | 1.00 | POLB (0.61) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL8477698 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL8477564 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL8477557 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL8482480 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL8477697 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL7310404 | 0.92 | POLB (0.62) | POLBFKBP1APSEN1PSEN2APH1B | |
| SCHEMBL20179 | 0.91 | POLB (0.64) | POLBFKBP1ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108786915-B | Preparation method and application of solid condensation catalyst | 山东新和成药业有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-108786915-A | A kind of preparation method and purposes of solid condensation catalyst | 山东新和成药业有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-108786915-B | Preparation method and application of solid condensation catalyst | 山东新和成药业有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-108786915-A | A kind of preparation method and purposes of solid condensation catalyst | 山东新和成药业有限公司 | 2018-11-13 | — | — | CN | disclosed |
| US-9512074-B2 | Radiolabeled inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2015-02-26 | — | — | US | disclosed |
| US-8895607-B2 | Inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2013-03-14 | — | — | US | disclosed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | POLB 3030/4885FKBP1A 3599/4885PSEN1 2460/4885 |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | POLB 2877/4885FKBP1A 3208/4885PSEN1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.