Sugi Predict

Sugi Predict / Compounds / SCHEMBL30564487

SCHEMBL30564487

SCHEMBL30564487

O=C(OCc1ccccc1)[C@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.61
▸ FKBP1A P62942 3/20 0.46
▸ PSEN1 P49768 1/20 0.46
▸ PSEN2 P49810 1/20 0.46
▸ APH1B Q8WW43 1/20 0.46
▸ NCSTN Q92542 1/20 0.46
▸ APH1A Q96BI3 1/20 0.46
▸ PSENEN Q9NZ42 1/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ HTR2C P28335 1/20 0.45
▸ CYP2C19 P33261 1/20 0.44
▸ PREP P48147 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2678864 1.00 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL23485199 1.00 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL7433978 1.00 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL8477698 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL8477564 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL8477557 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL8482480 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL8477697 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL7310404 0.92 POLB (0.62) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL20179 0.91 POLB (0.64) POLBFKBP1ASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-10-16 — — US disclosed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 — — US disclosed
EP-4538278-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Daewoong Pharmaceutical Co., Ltd. (KR) 2025-04-16 — — EP disclosed
CN-119213001-A Arginase inhibitors and pharmaceutical compositions comprising same 株式会社大熊制药 2024-12-27 — — CN disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US disclosed
WO-2023239166-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 대웅제약 2023-12-14 — — WO disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP POLB 4603/4885FKBP1A 1817/4885PSEN1 2585/4885
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ARG1, ARG2, PRMT1 POLB 3234/4885FKBP1A 4223/4885PSEN1 3625/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP POLB 4759/4885FKBP1A 1611/4885PSEN1 1391/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 POLB 4547/4885FKBP1A 926/4885PSEN1 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.