SCHEMBL7434

SCHEMBL7434

CC(C)(C)OC(=O)NCCCBr

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 1/20 0.61
GAA P10253 1/20 0.61
KMT2A Q03164 1/20 0.61
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
CA1 P00915 10/20 0.53
CA2 P00918 10/20 0.53
CA12 O43570 6/20 0.53
CA9 Q16790 6/20 0.53
EPHX1 P07099 1/20 0.45
HTT P42858 1/20 0.44
STK17B O94768 1/20 0.43
STK17A Q9UEE5 1/20 0.43
NPSR1 Q6W5P4 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229087 0.94 TDP1 (0.68) TDP1MEN1GAAKMT2AMAOA
SCHEMBL17286185 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL6449941 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL26634879 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1149061 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL19460948 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL18604607 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1041731 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL21596987 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7292779 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2757 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903678-B Iridium complex-nitroimidazole conjugate and preparation method and application thereof 东北师范大学 2025-06-24 CN claimed
WO-2025118255-A1 RADIOLABELED FAPI COMPLEX, PREPARATION METHOD THEREFOR, AND USE THEREOF 北京师范大学 2025-06-12 WO claimed
CN-120004862-A Compound, pharmaceutical composition and application thereof 山东大学 2025-05-16 CN claimed
CN-119978010-A Fluorescence enhancement anchoring agent based on fluoroboric dipyrrole-tetrazine dye for expansion microscopic imaging technology 厦门大学 2025-05-13 CN claimed
CN-119604492-A Radiolabeled FAPI complex and preparation method and application thereof 北京师范大学 2025-03-11 CN claimed
CN-119424686-A Preparation method of tumor double-targeting magnetic resonance/fluorescence imaging bimodal contrast agent 徐州医科大学 2025-02-14 CN claimed
CN-116731595-B Aminated tannic acid coating and preparation method and application thereof 大连理工大学 2025-01-10 CN claimed
CN-119119076-A Fluorescent probe for targeting BRD4 protein and preparation method and application thereof 华南理工大学 2024-12-13 CN claimed
CN-115650936-B Preparation method of (tert-butyl (3) -1, 4-diazapine-1-propyl) carbamate 天津药明康德新药开发有限公司 2024-11-01 CN claimed
CN-118184726-A Preparation method and application of platinum (IV) prodrug with glycyrrhetinic acid derivative as ligand 淮阴工学院 2024-06-14 CN claimed
CN-111393368-A Indenopyrazole hydrochloride derivative and preparation method and application thereof 山东大学 2020-07-10 CN claimed
CN-111374151-A Preparation method of multifunctional material containing TAA for sterilization, protein adsorption resistance and specific recognition 西南大学 2020-07-07 CN claimed
CN-110823974-A P-hydroxybenzaldehyde derivative probe and sulfur indium zinc/zinc oxide combined formaldehyde detection method 济南大学 2020-02-21 CN claimed
CN-110746410-A Leucine aminopeptidase and monoamine oxidase activated near-infrared fluorescent probe, synthetic method and biological application 湖南大学 2020-02-04 CN claimed
CN-107602417-A It is a kind of based on aggregation-induced emission mechanism can quick detection zinc ion fluorescence probe and preparation method and application 华南理工大学 2018-01-19 CN claimed
CN-103044311-B Multi-substituted indole compounds and preparation method and application thereof UNIV SHANDONG 2015-04-22 CN claimed
CN-102798712-B Fluorescent brightener CBS-X detection kit and preparation method thereof GUANGZHOU QUALITY SUPERVISION INSPECTION RES INST 2014-06-04 CN claimed
CN-103044311-A Multi-substituted indole compounds and preparation method and application thereof UNIV SHANDONG 2013-04-17 CN claimed
CN-102798712-A Fluorescent brightener CBS-X detection kit and preparation method thereof GUANGZHOU QUALITY SUPERVISION INSPECTION RES INST 2012-11-28 CN claimed
CN-102161688-A Cholesterol-structure-fragment-containing biocompatible synthesis liposomes as well as preparation method and application thereof SHANGHAI INST ORGANIC CHEM 2011-08-24 CN claimed