SCHEMBL229087

SCHEMBL229087

CC(C)(C)OC(=O)NCCCCBr

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
GAA P10253 1/20 0.59
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
CA1 P00915 7/20 0.55
CA2 P00918 7/20 0.55
CA12 O43570 6/20 0.55
CA9 Q16790 6/20 0.55
EPHX1 P07099 2/20 0.44
HTT P42858 1/20 0.43
STK17B O94768 1/20 0.43
STK17A Q9UEE5 1/20 0.43
CYP3A4 P08684 1/20 0.42
DRD2 P14416 1/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7292779 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL26634879 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL21596987 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL18604607 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL19460948 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL6449941 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL1149061 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL1041731 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL17286185 0.98 TDP1 (0.71) TDP1MEN1KMT2AGAAMAOA
SCHEMBL7434 0.94 TDP1 (0.65) TDP1MEN1KMT2AGAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102161688-A Cholesterol-structure-fragment-containing biocompatible synthesis liposomes as well as preparation method and application thereof SHANGHAI INST ORGANIC CHEM 2011-08-24 CN claimed
WO-2009064485-A1 ANTIOXIDANT FLAVONOID DERIVATIVES TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2009-05-22 WO claimed
US-20260137629-A1 Novel Lipids For Delivery Of Nucleic Acid Segments ASTRAZENECA AB (SE) 2026-05-21 US disclosed
WO-2026086944-A1 AMINOPYRIDONE MACROLIDE COMPOUND AND USE THEREOF 苏州信诺维医药科技股份有限公司 2026-04-30 WO disclosed
WO-2026086945-A1 PYRAZINE MACROLIDE COMPOUND AND USE THEREOF 苏州信诺维医药科技股份有限公司 2026-04-30 WO disclosed
EP-4731309-A1 KRAS PROTEOLYSIS TARGETING CHIMERAS Paq Therapeutics Inc. (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
EP-4722206-A1 BENZO(HETERO)CYCLOALKYL COMPOUNDS FOR ANDROGEN RECEPTOR-DEPENDENT DISEASES Haihe Biopharma Co., Ltd. (CN) 2026-04-08 EP disclosed
US-20260092071-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF UNIV MICHIGAN (US) 2026-04-02 US disclosed
EP-4712964-A1 COMPOUNDS AND FORMULATIONS USEFUL AS VACCINE ADJUVANTS Merck Sharp & Dohme LLC (US) 2026-03-25 EP disclosed
EP-4712979-A1 COMPOUNDS AND ADJUVANT FORMULATIONS USEFUL IN PNEUMOCOCCAL VACCINES Merck Sharp & Dohme LLC (US) 2026-03-25 EP disclosed
EP-0984777-A4 ARYLSUBSTITUTED PIPERAZINES USEFUL IN THE TREATEMENT OF BENIGN PROSTATIC HYPERLASIA ORTHO MCNEIL PHARM INC (US) 2001-04-25 EP disclosed
EP-1085879-A2 MULTIBINDING AGENTS THAT MODULATE THE 5-HT TRANSPORTER Advanced Medicine, Inc. (US) 2001-03-28 EP disclosed
WO-2001007036-A1 BICYCLIC ANTAGONISTS SELECTIVE FOR THE αvβ3 INTEGRIN AMERICAN HOME PRODUCTS CORPORATION (US) 2001-02-01 WO disclosed
CN-1264300-A Aryl substituted piperazines useful for treating benign prostatic hypertrophy ORTHO MCNELL PHARMACEUTICAL IN (US) 2000-08-23 CN disclosed
US-6071915-A SELECTIVELY INHIBIT BINDING TO THE ALPHA-1A ADRENERGIC RECEPTOR; N'-(ETHYL-2-(2-ISOPROPYLOXYPHENYL)PIPERAZIN-4-YL)-(1'(2-OXYPIPERIDINYL)ACETAMIDE AND DERIVATIVES ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2000-06-06 US disclosed
WO-1999063932-A9 MULTIBINDING AGENTS THAT MODULATE THE 5-HT TRANSPORTER ADVANCED MEDICINE INC (US) 2000-03-16 WO disclosed
EP-0984777-A1 ARYLSUBSTITUTED PIPERAZINES USEFUL IN THE TREATEMENT OF BENIGN PROSTATIC HYPERLASIA Ortho-Mcneil Pharmaceutical, Inc. (US) 2000-03-15 EP disclosed
WO-1999063932-A2 MULTIBINDING AGENTS THAT MODULATE THE 5-HT TRANSPORTER ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed
WO-1998051298-A1 ARYLSUBSTITUTED PIPERAZINES USEFUL IN THE TREATEMENT OF BENIGN PROSTATIC HYPERLASIA ORTHO-MCNEIL PHARMACEUTICAL INC. (US) 1998-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137629-A1 Novel Lipids For Delivery Of Nucleic Acid Segments LDLR, NPC1, NSUN2 TDP1 943/4885MEN1 3805/4885KMT2A 1911/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A TDP1 3694/4885MEN1 4679/4885KMT2A 1692/4885
US-20260092071-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF SMARCC2, SMARCC1, SMARCA2 TDP1 1888/4885MEN1 2647/4885KMT2A 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.