Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435042 | 1.00 | ADORA1 (0.68) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL4983923 | 1.00 | ADORA1 (0.68) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL4988512 | 0.78 | ADORA1 (0.71) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL4621677 | 0.77 | ADORA1 (1.00) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL3692016 | 0.77 | ADORA1 (0.70) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL8836134 | 0.77 | ADORA1 (0.78) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL6287806 | 0.76 | ADORA1 (0.73) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL7644015 | 0.76 | ADORA1 (0.71) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL8836301 | 0.76 | ADORA1 (0.76) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL8874884 | 0.76 | ADORA1 (0.76) | ADORA1ADORA2AADORA2BADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3173889-A | — | — | None | — | — | JP | disclosed |
| EP-0415456-B1 | Xanthine compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5525607-A | DIURETICS, BRONCHODILATORS, RENAL PROTECTING AGENTS | KYOWA HAKKO KOGYO CO., LTD (JP) | 1996-06-11 | — | — | US | disclosed |
| US-5290782-A | Bronchodilator agents, diuretics for renal protective agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| JP-H03173889-A | XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1991-07-29 | — | — | JP | disclosed |