Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434194 | 1.00 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1CYP1A2MME | |
| SCHEMBL8893214 | 0.96 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CYP1A2CPA1 | |
| SCHEMBL7434946 | 0.96 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CYP1A2CPA1 | |
| SCHEMBL8893218 | 0.96 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CYP1A2CPA1 | |
| SCHEMBL7434949 | 0.96 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CYP1A2CPA1 | |
| SCHEMBL7434959 | 0.91 | PPARA (0.46) | SLC1A3SLC1A2SLC1A1MMEACE | |
| SCHEMBL7434968 | 0.91 | PPARA (0.46) | SLC1A3SLC1A2SLC1A1MMEACE | |
| SCHEMBL8894789 | 0.91 | PPARA (0.46) | SLC1A3SLC1A2SLC1A1MMEACE | |
| SCHEMBL7445012 | 0.90 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1MMEACE | |
| SCHEMBL7445009 | 0.90 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |