Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 6/20 | 0.39 |
| ▸ | FPR2 | P25090 | 6/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445009 | 1.00 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL7432401 | 0.90 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL7432403 | 0.90 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL7434192 | 0.90 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL7434194 | 0.90 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL7434946 | 0.86 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8893218 | 0.86 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8893214 | 0.86 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7434949 | 0.86 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7434968 | 0.81 | PPARA (0.46) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |