Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716643 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL8523493 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL7237685 | 0.89 | ALDH1A1 (0.51) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL338742 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL21269769 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL21268824 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL21269594 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL19182697 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL395522 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 | |
| SCHEMBL21269412 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1AALDH1A1SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |